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Colonic length became shortened (35%) and colonic weight increased in colitic animals due to the accumulation of inflammatory cells and EGCG partially improved the length (9%) with no effect on weight compared to colitic animals (Table 1)
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Borthakur G, Tallman MS, Ofran Y, Foran J, Uy GL, DiPersion JF, Nagler A, Rowe JM, Showel MM, Altman JK, Peled A, Abraham M, Pereg Y, Vainstein A, Oberkovitz G, Aharon A, Bueso-Ramos C, Cortes JC, Andreeff M
This may suggest that the reductions seen from GLP-1s in both depression and anxiety are a direct effect, not subsequent to weight loss